Kwihlabathi elikhula rhoqo le-phytochemicals, i-berberine HCL ivelele njenge-molecule enomdla kakhulu. Ithatyathwe kuluhlu lwezityalo, kubandakanywa i-goldenseal, i-Oregon iidiliya, kunye ne-barberry, i-berberine HCL iye yagxila kwizifundo ezininzi zesayensi ngenxa yemisebenzi yayo eyahlukeneyo yebhayoloji.

I-Berberine HCL, okanye ityuwa ye-hydrochloride ye-berberine, i-pigment etyheli kunye noluhlu lwezicelo zonyango ezinokubakho. Iyaziwa nge-anti-inflammatory, anti-microbial, kunye ne-anti-diabetic properties, phakathi kwezinye. Ngaphezu koko, i-berberine HCL ibonise isithembiso kunyango lwezifo ezahlukahlukeneyo, kuquka i-Hepatitis B kunye ne-C, i-ulcerative colitis, kunye nesifo seswekile.

Iimpawu ze-antimicrobial ze-berberine HCL ziye zabhalwa ngokukodwa. Ibonakaliswe ukuba iyasebenza ngokuchasene noluhlu lweebhaktheriya, umngundo, kunye neentsholongwane, okwenza kube yinto enokuthi ibekho kwii-antibiotics eziqhelekileyo. Oku kubaluleke ngakumbi xa kujongwa ingxaki ekhulayo yokunganyangeki ngamayeza okubulala iintsholongwane.

Ukongeza kwizicelo zayo zonyango, i-berberine HCL nayo ifundwe ngendima enokubakho ekulahlekeni kobunzima. Olunye uphando lucebisa ukuba lunokunceda ukunciphisa amanqatha omzimba ngokuthintela i-lipogenesis (inkqubo yokuguqula iswekile ibe ngamafutha) kunye nokukhuthaza i-lipolysis (ukuqhekeka kwamafutha). Nangona kunjalo, uphando olongezelelweyo luyafuneka ukuqinisekisa ezi ziphumo kunye nokumisela idosi efanelekileyo yokulahlekelwa kwesisindo.

Ngaphandle kweenzuzo ezinokuthi zibekho, i-berberine HCL ayikho ngaphandle kwemida yayo. Iyaziwa ngokuba ne-bioavailability ephantsi, okuthetha ukuba ayifuntshwa lula ngumzimba. Ukongeza, ukusetyenziswa kwexesha elide kunokukhokelela kwi-berberine-resistant microorganisms, ukunciphisa ukusebenza kwayo ngokuhamba kwexesha. Ngoko ke, kubalulekile ukuba uphando olongezelelweyo lugxininise ekuphuculeni i-bioavailability ye-berberine HCL kunye nokujongana nemiba yokumelana nayo.

Ukuqukumbela, i-berberine HCL iyimolekyuli enomdla kunye noluhlu lwezicelo zonyango ezinokubakho. Imisebenzi yayo eyahlukeneyo yebhayoloji kunye nokusetyenziswa okunokwenzeka kunyango lwezifo ezahlukeneyo kuyenza ibe yindawo enomdla yophando. Nangona kunjalo, uphando oluninzi luyafuneka ukuze kuqondwe ngokupheleleyo iindlela zayo zokusebenza kunye nokwandisa ukusetyenziswa kwayo kwiisetingi zeklinikhi. Ngophando oluqhubekayo kunye nophuhliso, i-berberine HCL inokuthi ngenye imini ibe ngumdlali ophambili kwinkalo yeyeza lomntu.