1. Ii-anti-endothelin

Ikhutshwe kwi-chamomile yemifuno yaseYurophu, enokumelana ne-endothelin kwaye ithintele ukuveliswa kwee-melanocytes. Ukusasazwa okungalinganiyo kwe-endothelin eluswini yeyona nto iphambili ekhokelela ekwakhiweni kombala. Ii-Endothelin antagonists zinokuthintela i-endothelin.. tyrosinase kwaye zikhuthaze ukwahlukana kwee-melanocytes.

Izifundo zifumanise ukuba ii-endothelin antagonists ezithathwe kwizinto eziphilayo zasemanzini zinobuthi obuphantsi kwaye zinokuthintela ukwahluka kwe-endothelin kwi-melanocytes kunye nomsebenzi we-tyrosinase. Izifo ze-skin hyperpigmentation ezibangelwa kukwanda kwe--l zinokuba nethuba lokusetyenziswa.

2. I-Resveratrol kunye nezinto eziphuma kuyo

I-ResveratrolIfumaneka kakhulu kwiidiliya, iPolygonum cuspidatum, iVeratrum kunye nezinye izityalo, kwaye ithintela ukusebenza kwe-melanocytes kunye nomsebenzi we-tyrosinase ngendlela exhomekeke kuxinzelelo, ngaloo ndlela inciphisa ukwenziwa kwe-melanin. UJeong nabanye bafumanise ukuba ikwanxulunyaniswa neeproteni ezinxulumene ne-tyrosinase kwi-melanogenesis.

UJia Lili kunye nezinye izifundo zibonise ukuba i-resveratrol engaphandle inokuphucula umbala wolusu ngempumelelo, inefuthe elithile lokuba mhlophe, kwaye ayinazo iziphumo ezibi. I-Resveratrol ineengxaki zokungazinzi kunye nokungafumaneki kakuhle kwe-bioavailability. Izifundo zifumanise ukuba izinto eziphuma kuyo (i-pentaalkyl ether derivatives kunye ne-tetraester derivatives) zinokufumaneka okuphezulu kwe-bioavailability kwaye zinokuthintela ngcono ukwenziwa kwe-melanin. Inamathuba amaninzi okusetyenziswa kwi-cosmetics yokwenza mhlophe.

3. Isicatshulwa seCamellia

I-Camellia luhlobo lweCamellia losapho lweCamellia. UNakamura nabanye bafumanise ukuba i-camellia flower bud extract inokuthintela ukuveliswa kwe-melanin kwaye ikhuthaze ukwahluka kwe-fibroblast. UHuang Xiaofeng kunye nezinye izifundo bagqibe kwelokuba i-Dianshan tea branch kunye ne-leaf extract ingcono kune-arbutin ngokubhekiselele ekukhuleni kweeseli kunye nokuthintela umsebenzi we-tyrosinase, kwaye ineempawu ezingcono kune-arbutin. Luhlobo olutsha lwe-arhente yokwenza mhlophe ulusu kwaye luneendlela ezahlukeneyo zokusetyenziswa.

I-MelaninSi-ynthaseIi-inhibitor

1. I-Arbutin

Sisithinteli esibalulekileyo se-tyrosinase, esinokuthintela umsebenzi we-tyrosinase, sithintele ukwenziwa kwe-dopa kunye ne-dopaquinone, ngaloo ndlela sithintele ukuveliswa kwe-melanin, kwaye sinokunciphisa kakhulu umbala obangelwa yimitha ye-ultraviolet, kodwa sizinzile. Ukusebenza kakubi, kunye nokuziva ushushu okuthile.

Olu phononongo lufumanise ukuba i-arbutin enoxinzelelo lwe-3% ineempawu ezilungileyo, i-cytotoxicity ephantsi, ukucaphuka kunye ne-allergy, kwaye umda ophezulu woxinzelelo lwayo awunakudlula i-7%. Uxinzelelo oluphezulu lwe-arbutin luya kutshintsha umbala wolusu oluqhelekileyo. Isithako sayo sendalo esisebenzayo, i-glucopyranoside, inefuthe elinamandla lokuthintela i-tyrosinase yomntu kune-arbutin, kwaye ithatha indawo ye-arbutin kuba isebenza ngakumbi kwaye izinzile.

2. Isicatshulwa seLayicorice

Izithako zayo ezisebenzayo ikakhulu yi-liquiritin, i-isoliquiritin kunye ne-licorice flavonoids. I-Liquiritin yenza ukuba i-skin melanin isasazwe ngokulinganayo ngokusasaza i-aggregated melanin, kwaye ifezekisa isiphumo sokuba mhlophe; umsebenzi ophambili we-licorice flavonoids kukuthintela umsebenzi we-tyrosinase, i-DHICA oxidase kunye ne-dopa pigment intermutase.

Izifundo zifumanise ukuba iimveliso zokhathalelo lolusu lwezonyango eziqulethe i-licorice extract kunye ne-papain zinokunceda i-melasma kunye ne-hyperpigmentation emva kokudumba, kunye neempendulo ezingalunganga kangako, kwaye zineempawu ezithile .. kunye .. kunye .. iipropati. Uxinzelelo lwayo kwiimveliso zokwenza mhlophe yi-10% ukuya kwi-40%, kodwa umxholo wezithako ezisebenzayo kwi-licorice awuphezulu kwaye ukucocwa kunzima kwaye kubiza kakhulu.

3. Chuanxiong Extract

Izifundo zifumanise ukuba i-Chuanxiong extract inokuthintela ngempumelelo umsebenzi we-tyrosinase, ibonisa isiphumo sokuthintela esikhuphisanayo. I-ointment ye-Chuanqiong eyenziwe ngefomyula edibeneyo yee-emulsifiers ezahlukeneyo kunye ne-thickeners ezahlukeneyo, uphando malunga nokusebenza kwayo mhlophe lubonise ukuba i-ointment ye-Chuanqiong eyi-0.5% ~ 1.0% ineempawu zokuzinza okuhle, ukusebenza okuphezulu kunye nesiphumo esihle mhlophe.

4. Isicatshulwa seRhodiola Rosea

I-Salidroside kunye ne-flavonoids zezona zinto ziphambili ezisebenzayo, kwaye i-salidroside inokonakalisa ii-lipids kunye nee-membranes zeeseli ngemitha ye-ultraviolet. I-extract ingathintela ukwenziwa kwe-melanin kunye nomsebenzi we-tyrosinase, kwaye iyiarhente esebenzayo yokwenza mhlophe ulusu. Olu phononongo lufumanise ukuba i-1% kunye ne-5% ye-Rhodiola rosea extract ayizange ibangele iziphumo ezimbi emzimbeni womntu, kwaye sisithako esisebenzayo se-cosmetic esizinzileyo kwaye sinethuba elibanzi lokusetyenziswa kwe-cosmetic.

5. UAloin

Sisityalo esine-glycoprotein ephantsi enobunzima obuphantsi ekhutshwe kwi-aloe vera. Sithintela kakhulu ukwenziwa kwe-dopaquinone ngokuthintela indawo ye-oxidation ye-dopa ngokhuphiswano, kwaye sifezekisa uthintelo olungenakhuphiswano ngokuthintela ii-ion ze-copper kwindawo ye-hydroxylase ngokhuphiswano. Umsebenzi we-tyrosine hydroxylase. Ukongeza, i-aloin inokunciphisa ubumnyama besikhumba obubangelwa yimitha ye-ultraviolet, kwaye inesiphumo esihle sokulungisa ulusu emva kokuvezwa lilanga. I-Aloin ithanda amanzi kwaye ayinatyhefu. Ukuxuba i-aloin ne-arbutin kunokuphucula isiphumo sokuba mhlophe.

6. Iipolyphenols zezityalo

Ifumaneka kakhulu kwixolo, iingcambu, amagqabi kunye neziqhamo zezityalo, kwaye isiphumo sayo sokuba mhlophe sinxulumene kakhulu nokufunxwa kwayo yimisebe ye-ultraviolet, ukususwa kwe-antioxidant ye-free radicals, kunye nokuthintela imisebenzi ye-tyrosinase kunye ne-peroxidase. I-Ellagic acid yi-polyphenol yendalo ethathwe kwixolo le-pomegranate, ixolo kunye neziqhamo kunye nemifuno eyahlukeneyo. Ingathintela ukwanda kwe-melanocytes, ithintele umsebenzi we-melanocyte tyrosinase, inciphise ukwenziwa kwe-melanin, imisebe ye-Ultraviolet inesiphumo esinamandla sokufunxwa, esinokudlala indima ekukhuseleni ilanga okanye ekususeni ii-free radicals ngokufunxwa kwemisebe ye-ultraviolet. I-Plant polyphenol luhlobo lwesithako esisebenzayo, esinamathuba abanzi okuphuhliswa nokusetyenziswa kwezithambiso.

Iinkcukacha zoqhagamshelwano:
Shaanxi Ruiwo Phytochem Co.,Ltd.
Umphathi waphesheya: uJason
I-Mob: 0086-18629669868
I-imeyile:jason@ruiwophytochem.com
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